Effect of the addition of probiotic strains on blood metabolites in growing pigs
Abstract
Weaning is the most critical phase of the pig, causing intestinal disorders and diarrhea. To prevent this, have been used antibiotic growth promoters (AGP), generating medicine residues in the final product. Alternatively, bacteria that promote protein synthesis and lipid metabolism have been used probiotic. The aim was to identify changes in plasma metabolites in weaning pigs fed different probiotic strains. 80 piglets (weaned at 21 days) consumed two diets: Commercial diet with and without the addition of antibiotic (with added probiotic L. casei, L. acidophilus or E. faecium) in water. Blood samples were taken (15, 30 and 45 post-weaning) to determine plasma metabolite changes. An increase (P<0,05) in plasma levels of calcium, phosphorus, alkaline phosphatase and glucose was observed; also decreased levels of creatinine, triglycerides and ALT (alanine aminotransferase) in animals fed E. faecium, compared with those who consumed antibiotic. Probiotics (particularly E. faecium), can be considered as an alternative to the use of AGP in pig diets, by improving the state of digestive organs and act as natural growth promoters because they improve the metabolic state of the animal with positive changes in blood levels of calcium, phosphorus and glucose.Downloads
Languages:
es;enReferences
COLINA, J., RICO, D., ARAQUE, H., RUEDA, E., LEÓN, M., TOVAR, C. y ROSINI A. Hematología, metabolitos sanguíneos y peso de órganos de cerdos en crecimiento alimentados con Harina de Pijiguao (Bactris gasipaes H.B.K.) y Lisina. Revista Facultad de Ciencias Veterinarias, 51(1), 2010, p. 51-62.
BOUDRY, C., DEHOUX, J., PORTETELLE, D. and BULDGEN, A. Bovine colostrum as a natural growth promoter for newly weaned piglets: a review. Biotechnologie Agronomie Sociéte Environnement, 12(2), 2008, p. 157-170. 2008.
CAMPBELL, J., CRENSHAW, J. and POLO, J. The biological stress of early weaned piglets. Journal of Animal Science and Biotechnology, 4(1), 2013, p. 4-19.
SUGIHARTO, S., HEDEMANN, M. and LAURIDSEN, C. Plasma metabolomic profiles and immune responses of piglets after weaning and challenge with E. coli. Journal of Animal Science and Biotechnology, 5, 2014, p. 5-17.
RIEGER, J., JANCZYK, P., HÜNIGEN, H., NEUMANN, K. and PLENDL, J. Intraepithelial lymphocyte numbers and histomorphological parameters in the porcine gut after Enterococcus faecium NCIMB 10415 feeding in a Salmonella Typhimurium challenge. Veterinary Immunology and Immunopathology, 164, 2015, p. 40-50.
MISSOTTEN, J., MICHIELS, J. and DEGROOTE, J.D.S.S. Fermented liquid feed for pigs: an ancient technique for the future. Journal of Animal Science and Biotechnology, 6(1), 2015, p. 1-9.
WANG, X., YANG, F., LIU, C., ZHOU, H., WU, G., QIAO, S., LI, D. and WANG, J. Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic Aureomycin differentially affects the small intestinal proteomes of weanling piglets. Jourbal of Nutrition, 142(1), 2012, p. 7-13.
PLAZA-DÍAZ, J., GOMEZ-LLORENTE, C., FONTANA, L. and GIL, A. Modulation of immunity and inflammatory gene expression in the gut, in inflammatory diseases of the gut and in the liver by probiotics. World Journal of Gastroenterology, 2014, 20, p. 15632-15649.
COUNCIL FOR INTERNATIONAL ORGANIZATIONS OF MEDICAL SCIENCES (CIOMS). International Guiding Principles for Biomedical Research Involving Animals. Geneva (Italy): 1985, 28 p.
NATIONAL RESEARCH COUNCIL (NRC). The Nutrient Requirements of Swine. 11th ed. Washington DC (United States of America): National Academy Press, 2012, 400 p.
Statistical Analysis Systems Institute (SAS). SAS/STAT Users Guide. Version 9.2th. Cary, NC (United States of America): SAS Institute Inc, 2007, p 121.
XIAO, Y., WU, X., SUN, M., YANG, L., HONG, H., CHEN, G. and YANG, M. Response to dietary L-glutamine supplementation in weaned piglets: a serum metabolomic comparison and hepatic metabolic regulation analysis. Journal of Animal Science, 2012, 90(12), p. 4421-4430.
PONNAMPALAM, E., LEWANDOWSKI, P., NESARSTNAM, K., DUNSHEA, R. and GILL, H. Differential effects of natural palm oil, chemically- and enzymatically-modified palm oil on weight gain, blood lipid metabolites and fat deposition in a pediatric pig model. Nutrition Journal, 2011, 10, p. 1-7.
LYE, H., KHOO, Y., KARIM, A., RUSUL, G. and LIONG, T. Growth properties and cholesterol removal ability of electroporated Lactobacillus acidophilus BT 1088. Journal of Microbiology and Biotechnology, 2012, 22(7), p. 981-989.
GHANEM, K., BADAWY, I. and ABDEL-SALAM, A. Influence of yoghurt and probiotic yoghurt on the absorption of calcium, magnesium, iron and bone mineralization in rats. Milchwissenschaft, 2004, 59, p. 472-475.
PARVANEH, K., JAMALUDDIN, R., KARIMI, G. and ERFANI, R. Effect of probiotics supplementation on bone mineral content and bone mass density. Scientific World Journal, 2014, p. 1-6.
FERNÁNDEZ-GARCÍA, M., RODRÍGUEZ-FELICES, Y., GALLARDO-ESCUDERO, A., MATA-SOTO, C., PLANELLS, E., LISBONA, F., ALFÉREZ, J. y LÓPEZ-ALIAGA, I. Estudio del metabolismo proteico en una población de jóvenes sanos: factores asociados. ARS Pharmaceutica, 2010, 51(3), p. 401-406.
GONZALEZ, J.D. Alanina Aminotransferasa en Sparus aurata: control de la expresión génica mediante RNAi y de la actividad enzimática por aminooxiacetato [Tesis Doctoral Biotecnología]. Barcelona (España). Universidad de Barcelona, Facultad de Farmacia, Departamento de Bioquímica, 2012, p 186.
Spanish
English
.png)
